{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Adipose","PKSim.pred":0.6362,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.77341,"Method":"PK-Sim Standard","HTTK.pred":1.281}
{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Brain","PKSim.pred":0.69402,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.84369,"Method":"PK-Sim Standard","HTTK.pred":2.968}
{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Heart","PKSim.pred":0.6412,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.77948,"Method":"PK-Sim Standard","HTTK.pred":3.101}
{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Kidney","PKSim.pred":0.64324,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.78196,"Method":"PK-Sim Standard","HTTK.pred":6.551}
{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Liver","PKSim.pred":0.63553,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.77259,"Method":"PK-Sim Standard","HTTK.pred":6.31}
{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Lung","PKSim.pred":0.6428,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.78143,"Method":"PK-Sim Standard","HTTK.pred":4.776}
{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Muscle","PKSim.pred":0.64694,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.78647,"Method":"PK-Sim Standard","HTTK.pred":2.403}
{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Placenta","PKSim.pred":0.64004,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.77807,"Method":"PK-Sim Standard","HTTK.pred":1.201}
{"Drug":"Caffeine","DTXSID":"DTXSID0020232","Tissue":"Spleen","PKSim.pred":0.62622,"Blood-to-plasma concentration ratio":0.8226,"Tissue-to-blood partition coefficient":0.76127,"Method":"PK-Sim Standard","HTTK.pred":2.876}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Adipose","PKSim.pred":2.35363,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":3.08694,"Method":"Rodgers & Rowland","HTTK.pred":1.94142}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Brain","PKSim.pred":1.10384,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":1.44776,"Method":"Rodgers & Rowland","HTTK.pred":1.92902}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Heart","PKSim.pred":0.59094,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":0.77505,"Method":"Rodgers & Rowland","HTTK.pred":2.30527}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Kidney","PKSim.pred":0.63905,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":0.83816,"Method":"Rodgers & Rowland","HTTK.pred":4.28299}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Liver","PKSim.pred":0.63534,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":0.83329,"Method":"Rodgers & Rowland","HTTK.pred":4.65832}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Lung","PKSim.pred":0.86424,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":1.13351,"Method":"Rodgers & Rowland","HTTK.pred":1.88354}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Muscle","PKSim.pred":0.71601,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":0.9391,"Method":"Rodgers & Rowland","HTTK.pred":1.1949}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Placenta","PKSim.pred":0.20082,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":0.26338,"Method":"Rodgers & Rowland","HTTK.pred":0.40106}
{"Drug":"Midazolam","DTXSID":"DTXSID5023320","Tissue":"Spleen","PKSim.pred":0.36998,"Blood-to-plasma concentration ratio":0.76245,"Tissue-to-blood partition coefficient":0.48525,"Method":"Rodgers & Rowland","HTTK.pred":1.49213}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Adipose","PKSim.pred":4.53323,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":5.1999,"Method":"Rodgers & Rowland","HTTK.pred":1.81689}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Brain","PKSim.pred":2.09269,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":2.40045,"Method":"Rodgers & Rowland","HTTK.pred":0.65297}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Heart","PKSim.pred":1.00166,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":1.14897,"Method":"Rodgers & Rowland","HTTK.pred":1.66019}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Kidney","PKSim.pred":1.12311,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":1.28827,"Method":"Rodgers & Rowland","HTTK.pred":2.1275}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Liver","PKSim.pred":1.20912,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":1.38694,"Method":"Rodgers & Rowland","HTTK.pred":2.81776}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Lung","PKSim.pred":1.44528,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":1.65783,"Method":"Rodgers & Rowland","HTTK.pred":0.29832}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Muscle","PKSim.pred":1.32484,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":1.51968,"Method":"Rodgers & Rowland","HTTK.pred":0.42328}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Placenta","PKSim.pred":0.24236,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":0.278,"Method":"Rodgers & Rowland","HTTK.pred":0.20434}
{"Drug":"Nifedipine","DTXSID":"DTXSID2025715","Tissue":"Spleen","PKSim.pred":0.71007,"Blood-to-plasma concentration ratio":0.87179,"Tissue-to-blood partition coefficient":0.8145,"Method":"Rodgers & Rowland","HTTK.pred":0.54943}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Adipose","PKSim.pred":1.09577,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":0.87754,"Method":"Rodgers & Rowland","HTTK.pred":2.61009}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Brain","PKSim.pred":2.45524,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":1.96626,"Method":"Rodgers & Rowland","HTTK.pred":5.61895}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Heart","PKSim.pred":6.05995,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":4.85307,"Method":"Rodgers & Rowland","HTTK.pred":6.02037}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Kidney","PKSim.pred":12.7715,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":10.22798,"Method":"Rodgers & Rowland","HTTK.pred":12.68512}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Liver","PKSim.pred":11.77548,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":9.43032,"Method":"Rodgers & Rowland","HTTK.pred":11.66397}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Lung","PKSim.pred":9.87976,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":7.91214,"Method":"Rodgers & Rowland","HTTK.pred":9.54245}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Muscle","PKSim.pred":7.19892,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":5.76521,"Method":"Rodgers & Rowland","HTTK.pred":4.09428}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Placenta","PKSim.pred":3.22157,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":2.57997,"Method":"Rodgers & Rowland","HTTK.pred":1.77733}
{"Drug":"Metoprolol","DTXSID":"DTXSID2023309","Tissue":"Spleen","PKSim.pred":8.34269,"Blood-to-plasma concentration ratio":1.24868,"Tissue-to-blood partition coefficient":6.68119,"Method":"Rodgers & Rowland","HTTK.pred":5.71315}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Adipose","PKSim.pred":2.55294,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":2.00169,"Method":"Poulin & Theil","HTTK.pred":5.86861}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Brain","PKSim.pred":6.95169,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":5.45062,"Method":"Poulin & Theil","HTTK.pred":2.43869}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Heart","PKSim.pred":1.83896,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":1.44187,"Method":"Poulin & Theil","HTTK.pred":6.59788}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Kidney","PKSim.pred":2.74563,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":2.15277,"Method":"Poulin & Theil","HTTK.pred":8.04289}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Liver","PKSim.pred":4.40411,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":3.45313,"Method":"Poulin & Theil","HTTK.pred":9.5494}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Lung","PKSim.pred":0.78308,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":0.61399,"Method":"Poulin & Theil","HTTK.pred":2.42578}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Muscle","PKSim.pred":2.77746,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":2.17773,"Method":"Poulin & Theil","HTTK.pred":1.72602}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Placenta","PKSim.pred":0.41192,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":0.32297,"Method":"Poulin & Theil","HTTK.pred":0.66717}
{"Drug":"Ondansetron","DTXSID":"DTXSID8023393","Tissue":"Spleen","PKSim.pred":2.79521,"Blood-to-plasma concentration ratio":1.27539,"Tissue-to-blood partition coefficient":2.19165,"Method":"Poulin & Theil","HTTK.pred":2.41225}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Adipose","PKSim.pred":0.66282,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":0.71305,"Method":"Rodgers & Rowland","HTTK.pred":2.27884}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Brain","PKSim.pred":1.19858,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":1.28941,"Method":"Rodgers & Rowland","HTTK.pred":4.67967}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Heart","PKSim.pred":3.34798,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":3.60168,"Method":"Rodgers & Rowland","HTTK.pred":4.76582}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Kidney","PKSim.pred":7.14559,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":7.68706,"Method":"Rodgers & Rowland","HTTK.pred":9.75218}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Liver","PKSim.pred":6.56191,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":7.05915,"Method":"Rodgers & Rowland","HTTK.pred":9.18704}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Lung","PKSim.pred":5.54483,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":5.965,"Method":"Rodgers & Rowland","HTTK.pred":7.9706}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Muscle","PKSim.pred":3.88677,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":4.1813,"Method":"Rodgers & Rowland","HTTK.pred":3.36674}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Placenta","PKSim.pred":1.63951,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":1.76375,"Method":"Rodgers & Rowland","HTTK.pred":1.03862}
{"Drug":"Granisetron","DTXSID":"DTXSID0023111","Tissue":"Spleen","PKSim.pred":4.62661,"Blood-to-plasma concentration ratio":0.92956,"Tissue-to-blood partition coefficient":4.9772,"Method":"Rodgers & Rowland","HTTK.pred":4.38676}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Adipose","PKSim.pred":7.90546,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":11.66006,"Method":"PK-Sim Standard","HTTK.pred":1.52933}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Brain","PKSim.pred":1.12462,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":1.65874,"Method":"PK-Sim Standard","HTTK.pred":0.65063}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Heart","PKSim.pred":1.04324,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":1.53871,"Method":"PK-Sim Standard","HTTK.pred":1.38558}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Kidney","PKSim.pred":0.57164,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":0.84313,"Method":"PK-Sim Standard","HTTK.pred":1.91468}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Liver","PKSim.pred":0.74147,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":1.09362,"Method":"PK-Sim Standard","HTTK.pred":2.50177}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Lung","PKSim.pred":0.16095,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":0.23739,"Method":"PK-Sim Standard","HTTK.pred":0.28799}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Muscle","PKSim.pred":0.18931,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":0.27922,"Method":"PK-Sim Standard","HTTK.pred":0.39188}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Placenta","PKSim.pred":0.10158,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":0.14982,"Method":"PK-Sim Standard","HTTK.pred":0.18072}
{"Drug":"Diazepam","DTXSID":"DTXSID4020406","Tissue":"Spleen","PKSim.pred":0.22179,"Blood-to-plasma concentration ratio":0.678,"Tissue-to-blood partition coefficient":0.32712,"Method":"PK-Sim Standard","HTTK.pred":0.50929}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Adipose","PKSim.pred":0.17003,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.19771,"Method":"Rodgers & Rowland","HTTK.pred":0.66215}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Brain","PKSim.pred":0.72934,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.84808,"Method":"Rodgers & Rowland","HTTK.pred":1.03}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Heart","PKSim.pred":0.55426,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.64449,"Method":"Rodgers & Rowland","HTTK.pred":1.38763}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Kidney","PKSim.pred":0.65831,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.76548,"Method":"Rodgers & Rowland","HTTK.pred":3.25879}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Liver","PKSim.pred":0.62839,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.73069,"Method":"Rodgers & Rowland","HTTK.pred":3.40089}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Lung","PKSim.pred":0.57264,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.66586,"Method":"Rodgers & Rowland","HTTK.pred":1.24362}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Muscle","PKSim.pred":0.71401,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.83025,"Method":"Rodgers & Rowland","HTTK.pred":0.98422}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Placenta","PKSim.pred":0.79734,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.92715,"Method":"Rodgers & Rowland","HTTK.pred":0.91136}
{"Drug":"Metronidazole","DTXSID":"DTXSID2020892","Tissue":"Spleen","PKSim.pred":0.53851,"Blood-to-plasma concentration ratio":0.85999,"Tissue-to-blood partition coefficient":0.62618,"Method":"Rodgers & Rowland","HTTK.pred":1.18831}